BeingMeredith Grey(played byEllen Pompeo) isn’t easy.

Her mother, once a brilliant surgeon, is diagnosed with Alzheimer’s shortly after Meredith becomes an intern.

She operates on a patient who dies, then discovers that the patient is a friend.

ellen pompeo grey’s anatomy

She loses the love of her life when her husband is involved in a fatal car crash.

Her father blames her for the death of her stepmother.

It would be a stretch to say these events have left Meredith a happy and optimistic person.

grey’s anatomy cast

In short, she’s become one of us.

This episode was also a high point for creatorShonda Rhimes, who received an Emmy nomination for the episode.

sandra oh and ellen pompeo