He even made a comment about beloved actor Keanu Reeves that left some fans reeling.

And that’s called a Hail Mary.

No one survives that," the star later toldPeopleof the ordeal.

Matthew Perry poses for a photograph.

However, his remarks about Reeves were highly publicized and led to Perry sharing a public apology.

If you, or anyone you know, is struggling with addiction issues, help is available.

It always seems to be the really talented guys who go down.

Matthew Perry and Keanu Reeves posing in split image

Perry later revealed that he had taken Reeves' name out of his memoir.

For his part, Reeves stayed quiet about the situation, never publicly commenting on the feud rumors.

The “Friends” alum admitted that he had intimate moments with Gwyneth Paltrow and Valerie Bertinelli.

Matthew Perry on the red carpet.

However, the actor says that the film was probably his best movie.

Perry has been through a lot of ups and downs in his life and has made some controversial decisions.